The designation of Avi Kwa Ame as Nevada’s 4th National Monument is supported by the following entities:
- Fort Mojave Indian Tribe
- Moapa Band of Paiutes
- Las Vegas Paiute Tribe
- Inter-Tribal Council of Nevada
- Inter-Tribal Council of Arizona
- Congresswoman Dina Titus
- Congresswoman Susie Lee
- Lieutenant Governor of Nevada Lisa Cano Burkhead
- Boulder City Chamber of Commerce
- Boulder City Council
- Searchlight Town Advisory Board
- Laughlin Town Advisory Board
- Laughlin Chamber of Commerce
- Laughlin Tourism Commission
- Clark County
- City of Henderson
- Conservation Lands Foundation
- Defenders of Wildlife
- Friends of Nevada Wilderness
- Friends of Sloan Canyon
- Friends of Walking Box Ranch
- Get Outdoors Nevada
- International Dark-Sky Association
- Las Vegas Indian Center
- National Park Conservation Association
- Nevada Conservation League
- Nevada Wildlife Federation
- Native American Alliance, CSN
- Native American Student Association, UNLV
- Protectors of Tule Springs
- Save Red Rock
- The Sierra Club Toiyabe Chapter
- The Wilderness Society